颜玉蓉,女,1970年出生,医学博士,教授,硕士生导师。
先后毕业于四川大学(原成都科技大学)生物化学工程专业和重庆医科大学临床检验诊断学专业,分别获得工学学士和医学科学博士学位。
长期从事临床检验诊断学、生物分析化学的教学及科研工作。作为负责人主持了国家自然科学基金“表面等离子共振microRNA 快速高灵敏检测新技术的研究及其在胃癌诊疗中的应用”、重庆市科委重点实验室专项“电化学核酸适体传感器用于粘蛋白MUC1的快速超灵敏检测”、重庆市自然科学基金“表面等离子共振生物传感器用于miRNA快速、超灵敏检测的研究”、重庆市教委“雏鹰计划”项目等。参与国家自然科学基金一审、河北省科技奖励评审、天津市自然科学基金评审等工作。Biosensors and Bioelectronics、Analytica Chimica Acta、Microchimica Acta等期刊审稿人。
主要研究领域:生物电分析化学、表面等离子共振与分子诊断、生物传感和纳米技术
主要科研论文
2018年
1.Wei Diao#, Min Tang#, Shijia Ding,Xinmin Li, Wenbin Cheng, Fei Mo, Xiaoyu Yan, Hongmin Ma,Yurong Yan*, Highlysensitive surface plasmon resonance biosensor for the detection of HIV-relatedDNA based on dynamic and structural DNA nanodevices, Biosensors andBioelectronics, 2018, 2018(100): 228-234.
2.WenbinCheng#, YeZhang#, HuaYu,WeiDiao, FeiMo, BoWen, WeiCheng,YurongYan*, An enzyme-freecolorimetric biosensing strategy for ultrasensitive and specific detection ofmicroRNA based on mismatched stacking circuits, Sensors andActuators B: Chemical, 2018, 255(3): 3298-3304.
2016年
3.Jianbo Li, Pinhua Lei, Shijia Ding,Ye Zhang, Jianru Yang, Quan Cheng,YurongYan*, An enzyme-free surface plasmonresonance biosensor for real-time detecting microRNA based on allosteric effectof mismatched catalytic hairpin assembly, Biosensors and Bioelectronics, 2016,77: 435-441.
4.Yurong Yan, Shijia Ding, Dan Zhao,Rui Yuan, Yuhong Zhang, Wei Cheng*, Direct ultrasensitive electrochemical biosensing of pathogenic DNAusing homogeneous target-initiated transcription amplification,Scientific Reports, 2016,6: 18810.
5.Wei Diao#, Min Tang#, XiaojuanDing, Ye Zhang, Jianru Yang, Wenbin Cheng, Fei Mo, Bo Wen, Lulu Xu,YurongYan*, Microchimica Acta,2016, 183(9): 2563-2569.
6.Jianru Yang#, Min Tang#, Wei Diao, WenbinCheng, Ye Zhang,Yurong Yan*, Electrochemical strategy for ultrasensitivedetection of microRNA based on MNAzyme-mediated rolling circle amplification ona gold electrode, Microchimica Acta, 2016, 183(11): 3061-3067.
2015年
7.Yurong Yan, Bo Shen, Hong Wang, Xue Sun, Wei Cheng, HuaZhao, Huangxian Ju, Shijia Ding*, A novel and versatile nanomachine forultrasensitive and specific detection of microRNAs based on molecular beaconinitiated strand displacement amplification coupled with catalytic hairpin assemblywith DNAzyme formation, Analyst, 2015, 140(16):5469-74。
8.Wenhong Chen#,Yurong Yan#, Ye Zhang, Xuemei Zhang, YibingYin*, Shijia Ding*, DNA transducer-triggered signal switch for visualcolorimetric bioanalysis, Scientific Reports, 10;5:11190。
9.Ye Zhang#,Yurong Yan#, Wenhong Chen, Wei Cheng, Shengqiang Li, Xiaojuan Ding, Dandan Li, HongWang, Huangxian Ju, Shijia Ding*, A simpleelectrochemical biosensor for highly sensitive and specific detection ofmicroRNA based on mismatched catalytic hairpin assembly, Biosensors and Bioelectronics, 2015, 2015(68): 243-249。
10.Chenyang Tao#,Yurong Yan#, Hua Xiang, Dan Zhu, Wei Cheng, HuangXian Ju, Shijia Ding*, A new mde forhighly sensitive and specific detection of DNA based on exonucleaseIII-assisted target recycling amplification and mismatched catalytic hairpinassembly, ChemicalCommunications, 2015, 51(20): 4220-4222.
11.Pinhua Lei, Hua Tang, Shijia Ding, Xiaojuan Ding, Dan Zhu, Bo Shen, Quan Cheng,Yurong Yan*, Determination of the invA gene of Salmonella using surfaceplasmon resonance along withstreptavidin aptamer amplification, Microchim Acta, 2015, 182(1-2): 289-296.
2014年
12.Dan Zhu#,Yurong Yan#, Pinhua Lei, Bo Shen, Wei Cheng, Huangxian Ju, Shijia Ding*, A novelelectrochemical sensing strategy for rapid and ultrasensitive detection ofSalmonella by rolling circle amplification and DNA-AuNPs probe,Analytica Chimica Acta, 2014, 846: 44-50。
13.Yahui Li#,Yurong Yan#, Yaning Lei, Dan Zhao, Taixian Yuan, Decai Zhang, Wei Cheng, Shijia Ding*, Surface plasmon resonance biosensor for label-free andhighly sensitive detection of point mutation using polymerizationextensionreaction, Colloids andSurfaces B: Biointerfaces, 2014, 120: 15-20。
2013年
14.Yurong Yan#, Dan Zhao, Taixian Yuan, Jun Hu, Decai Zhang, Wei Cheng, Wei Zhang, Shijia Ding*, A simple and highly sensitive electrochemical biosensor formicroRNA detection using target-assisted isothermal exponential amplificationreaction, Electroanalysis, 2013, 25(10): 2354-2359。
15.Decai Zhang#,Yurong Yan#, Wei Cheng, Wei Zhang, Yahui Li, Shijia Ding*, Huangxian Ju, Streptavidin-enhancedsurface plasmon resonance biosensor for highly sensitive and specific detectionof microRNA, MicrochimicaActa, 2013, 180(5-6): 397-403.
2012年
16.Decai Zhang#,Yurong Yan#, Qing Li, Tianxiao Yu, Wei Cheng, Long Wang, Huangxian Ju, Shijia Ding*, Label-free and high-sensitive detection of Salmonella usinga surface plasmon resonance DNA-based biosensor, Journal of Biotechnology, 2012, 160(3-4): 123-128.
编写专著、教材等
1. 参编科学出版社《生物分析化学》(2007年),ISBN:7030183495,主编:鞠熀先,邱宗荫,丁世家。
2. 参编科学出版社《临床蛋白质组学》(2008年),ISBN:9787030206268,主编:邱宗荫,尹一兵。
联系信息
重庆医科大学检验医学院,临床检验诊断学教育部重点实验室,400016
Tel/Fax, +86-23-68485240;
E-mail, yanyurong1@sina.com