左国伟，医学博士、副教授、硕士研究生导师
E-mail地址：gwzuo@qq.com
个人网站：www.zuoguowei.com
教学方面：
通过医学检验专业技术职称考试（中级）及美国临床病理协会ASCP的MedicalLaboratoryScientist认证考试。主讲实验诊断学，参与留学生实验诊断学的英文授课，兼任郑州大学医学检验专业《专业英语》老师。参与翻译《实验室检验和诊断手册》（人民军医出版社）和Henry’s Clinical Diagnosis and Management by Laboratory Methods《Henry临床实验诊断学》（人民卫生出版社）。
科研方面：
以前主要从事骨肉瘤相关的基础研究；目前主要的主要研究兴趣是通过比色法和人工智能技术相结合检测生物标志物。
教育经历：
1997年9月——2002年7月张家口医学院临床医学本科
2002年9月——2005年7月重庆医科大学人体解剖与组织胚胎学硕士研究生导师：赖国旗
2007年9月——2010年7月重庆医科大学临床检验诊断学博士研究生导师：何通川
2008年8月——2010年3月美国芝加哥大学医学中心分子肿瘤实验室访问学者
发表论文：
1.Zhangxu Zhou, Shujuan Yan, Ruyi Zhang, Hao Wang, Ziqian Ye, Zhilun Zhang, Keyu Li,Guowei Zuo*.CCN2/CTGF mediates proliferation and migration of human osteosarcoma cells induced by CXCL12/CXCR4-Akt-αvβ3 pathway via MSCs in bone marrow microenvironment. Under review.（*通讯作者）
2.Dan Liu, Hao Wang, Zhangxu Zhou, Xiaohan Mao, Ziqian Ye, Zhilun Zhang, Shixin Tu, Yanlai Zhang, Xue Cai, Xin Lan, Zhang Zhang, Baoru Han*,Guowei Zuo*. Integrated bioinformatic analysis and experiment confirmation of the antagonistic effect and molecular mechanism of ginsenoside Rh2 in metastatic osteosarcoma.Journal of Pharmaceutical and Biomedical Analysis. 2021, 201:114088.（*共同通讯作者）
3.Xiaohan Mao, Yaqian Jin, Tianyu Feng, Hao Wang, Dan Liu, Zhangxu Zhou, Qi Yan, Huini Yang, Jieru Yang, Jing Yang, Yan Ye, Yuxi Su*, andGuowei Zuo*. Ginsenoside Rg3 Inhibits the Growth of Osteosarcoma and Attenuates Metastasis through the Wnt/β-Catenin and EMT Signaling Pathway.Evidence-Based Complementary and Alternative Medicine. 2020, 2020:6065124. (*共同通讯作者)
4.Tianyu Feng, Zhongkai Zhu, Yaqian Jin, Hao Wang, Xiaohan Mao, Dan Liu, Yiling Li, Lixia Lu andGuowei Zuo*. The microRNA‑708‑5p/ZEB1/EMT axis mediates the metastatic potential of osteosarcoma.Oncology Reports. 2020, 43: 491-502. (*通讯作者)
5.Xin Su, Yalin Wei, Junjie Cao, Xiulin Wu, Daiyong Mou, Jinyong Luo, Aifang Li,Guo-Wei Zuo*and Min Tang*. CCN3 and DLL1 co-regulate osteogenic differentiation of mouse embryonic fibroblasts in a Hey1-dependent manner.Cell Death & Disease. 2018; 9(12): 1188. (*共同通讯作者)
6.Mengyi Hou, Zhenglan Huang, Sicheng Chen, Hao Wang, Tianyu Feng, Shujuan Yan, Yuxi Su andGuowei Zuo*. Synergistic anti-tumor effect of suberoylanilide hydroxamic acid and cisplatin in osteosarcoma cells.Oncology Letters. 2018, 16: 4663-4670. (*通讯作者)
7.Hao Wang, Min Tang, Liping Ou, Mengyi Hou, Tianyu Feng, Yu-E Huang, Yaqian Jin, Heng Zhan &Guowei Zuo*. Biological analysis of cancer specific microRNAs on function modeling in osteosarcoma.Scientific Reports. 2017;7(1):5382. doi: 10.1038/s41598-017-05819-7. (*通讯作者)
8.Juan Yao, zhang zhang, Yingze Zhao, Wanli Jing andGuowei Zuo*. Double-stranded probe modified AuNPs for sensitive and selective detection of microRNA 30a in solution and live cell.RSC Advances. 2016, 6:38869-38874. DOI: 10.1039/C6RA05131F. (*通讯作者)
9.Juan Yao, Yaguang Weng, Shujuan Yan, Mengyi Hou, Hao Wang, Qiong Shi andGuowei Zuo*. NOV inhibits proliferation while promoting apoptosis and migration in osteosarcoma cell lines through p38/MAPK and JNK/MAPK pathways.Oncology Reports. 2015, 34(4): 2011-2021. (*通讯作者) (IF:2.486)
10.Shi Q, Li J, Feng Z, Zhao L, Luo L, You Z, Li D, Xia J,Zuo G*, Chen D*. Effect of ginsenoside Rh2 on the migratory ability of HepG2 liver carcinoma cells: Recruiting histone deacetylase and inhibiting activator protein 1 transcription factors.Molecular Medicine Reports. 2014, 10(4):1779-1785. DOI: 10.3892/mmr.2014.2392 (*共同通讯作者) (IF:1.692)
专利：
1)左国伟,刘丹,张章.基于等温指数扩增的microRNA生物传感器. 2020-11-11.中国, CN202011256208.1
2)左国伟,周章旭,叶紫芊,韩宝如,郭红丽.一种基于纳米金颗粒（AuNPs）适配体偶联比色和人工智能算法检测母乳中残留阿莫西林的方法.发明专利，已提交
